CEF (UMNSAH/DF-1) in SP CDM

CellCrine

The first single-protein Chemically Defined Medium that beats FBS for less than 20 ¢ per Liter

Understanding and harnessing the power of cells

It is well established that nearly every cell type can produce secreted factors.

Biochemical, structural and functional understanding of secreted factors has enabled us to develop a Single rProtein Chemically Defined Medium for many cell types.

We have identified and optimized critical media components that induce potent cell signaling.

This discovery allows us to utilize only one rProtein, eliminating the need for growth factors or other recombinant proteins.

CellCrine’s SP CDM validated on more than 20 different cell types, including CEF/DF1 and iBSC cells.

Same core formulation SP CDM for Muscle Cells, Fibroblasts, Fat cells, CHO, Vero, MRC5, MDCK, HeLa, HEK293, Keratinocytes, C2C12, C912, CEF, BMC, iBSC, CEF/DF1 cells, …

The cell culture media is the most important factor underlying the success of the cultivated meat industry.  Good Food Institute

Reducing or eliminating the need for recombinant growth factors offer part of the solution to bringing cultivated meat toward price parity with conventional meat. Good Food Institute

CellCrine’s Single rProtein Chemically Defined Media (SP CDM) that has demonstrated superior performance to Fetal Bovine Serum (FBS) for many cell types, including Chicken Embryo Fibroblasts (UMNSAH/DF-1*) and Bovine Muscle cell line from Tufts University ( iBSC ).

*This cell line is notably used by Good Meat in Singapore.

Cracking the code

CellCrine has achieved a significant milestone after 30 years of dedicated research and development. We've developed a groundbreaking Single rProtein Chemically Defined (SP-CDM) technology that outperforms both Fetal Bovine Serum (FBS) and all commercially available basal media, all for less than 20¢ per liter.

CellCrine's SP-CDM allows cells to be seeded in a standard cell culture-grade vessel providing them with the essential nutrients and building blocks needed to thrive and outperform FBS.

CMI companies face the challenge of entering established, cost-sensitive markets where consumer loyalty to traditional animal products is strong. To succeed, these companies need a scaling strategy that prioritizes long-term profitability. This means focusing on competitive pricing, superior taste, and seamless integration into existing consumer habits.

CellCrine has developed SP-CDM to address these challenges and make cultivated meat a market reality.

We aim to offer the most cost-effective CDM to the CMI, BioPharma, and Scientific communities.

Request a free sample at: info@cellcrine.com